Assay Report Card

Basic Information

ID: ALA4411815

Type: Functional

Description: Antiinflammatory activity in human PBMC assessed as reduction in anti-CD3/CD28 antibody-stimulated TNF-alpha expression at 250 nM preincubated for 1 hr followed by anti-CD3/CD28 antibody stimulation measured after 24 hrs in presence of KZR-504 by ELISA

Organism: Homo sapiens

Cell type: PBMC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
632.853.903.90