Toxicity in nude mouse xenografted with human A549/TR cells expressing NQO1 assessed as damage to spleen at 15 to 30 mg/kg, iv treated every other day...

Basic Information

ID: ALA4411894

Type: Toxicity

Description: Toxicity in nude mouse xenografted with human A549/TR cells expressing NQO1 assessed as damage to spleen at 15 to 30 mg/kg, iv treated every other day for 3 weeks by hematoxylin and eosin staining based optical microscopic analysis

Format: BAO_0000218

Organism: Mus musculus

Tissue: Spleen

Cell type: A549/TR

Target:  ADMET(ALA612558)

Document:  ALA4411270

Toxicity in nude mouse xenografted with human A549/TR cells expressing NQO1 assessed as damage to spleen at 15 to 30 mg/kg, iv treated every other day for 3 weeks by hematoxylin and eosin staining based optical microscopic analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
268.181.711.71