Basic Information
ID: ALA4411916
Type: Binding
Description: Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Androgen Receptor(ALA1871)
Document: ALA4411271
Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4411916
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.38 | 2.88 | 2.88 |
| 464.44 | 3.99 | 3.99 |
| 389.33 | 3.22 | 3.22 |
| 477.44 | 3.53 | 3.53 |
| 407.37 | 3.47 | 3.47 |
| 407.37 | 3.47 | 3.47 |
| 439.42 | 4.67 | 4.67 |
| 463.46 | 5.59 | 5.59 |
| 419.38 | 4.37 | 4.37 |
| 389.38 | 3.33 | 3.33 |
| 405.35 | 4.06 | 4.06 |
| 387.36 | 3.92 | 3.92 |
| 447.90 | 5.36 | 5.36 |
| 459.42 | 4.10 | 4.10 |
| 434.72 | 3.73 | 3.73 |
| 447.90 | 5.36 | 5.36 |
| 405.35 | 4.06 | 4.06 |
| 466.26 | 4.68 | 4.68 |
| 481.45 | 5.73 | 5.73 |
| 425.36 | 3.61 | 3.61 |
| 405.35 | 4.06 | 4.06 |
| 371.80 | 3.70 | 3.70 |
| 499.44 | 5.87 | 5.87 |
| 405.35 | 4.06 | 4.06 |
| 371.80 | 3.70 | 3.70 |
| 481.45 | 5.73 | 5.73 |
| 391.81 | 3.24 | 3.24 |
| 373.81 | 3.10 | 3.10 |
| 373.81 | 3.10 | 3.10 |
| 449.91 | 4.77 | 4.77 |
| 373.81 | 3.10 | 3.10 |
| 513.26 | 4.53 | 4.53 |
| 432.36 | 3.83 | 3.83 |
| 371.80 | 3.70 | 3.70 |
| 397.35 | 3.52 | 3.52 |
| 413.36 | 3.19 | 3.19 |
| 478.47 | 4.94 | 4.94 |
| 371.80 | 3.70 | 3.70 |
| 432.36 | 3.83 | 3.83 |
| 431.37 | 3.62 | 3.62 |
| 371.80 | 3.70 | 3.70 |