Basic Information
ID: ALA4412513
Type: ADME
Description: Inhibition of CYP3A4 in liver microsomes (unknown origin) using ketoconazole as substrate preincubated for 5 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4411291
Inhibition of CYP3A4 in liver microsomes (unknown origin) using ketoconazole as substrate preincubated for 5 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4412513
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 520.64 | 6.41 | 6.41 |