ID: ALA4412514
Type: ADME
Description: Inhibition of CYP1A2 in liver microsomes (unknown origin) using alpha-naphthoflavone as substrate preincubated for 5 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Bioactivity
Activity Types for Assay ALA4412514
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
520.64 | 6.41 | 6.41 |