Basic Information
ID: ALA4412720
Type: Binding
Description: Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins followed by substrate addition and measured after 2 hrs by TLC or HPLC method
Format: BAO_0000220
Organism: Homo sapiens
Subcellular Fraction: Lysate
Target: Phosphatidylcholine:ceramide cholinephosphotransferase 2(ALA3112379)
Document: ALA4411297
Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins followed by substrate addition and measured after 2 hrs by TLC or HPLC method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4412720
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.36 | 4.52 | 4.52 |
| 314.39 | 4.94 | 4.94 |
| 289.38 | 4.88 | 4.88 |
| 332.40 | 3.90 | 3.90 |
| 357.42 | 3.98 | 3.98 |
| 304.35 | 3.91 | 3.91 |
| 328.42 | 5.12 | 5.12 |
| 426.90 | 4.98 | 4.98 |
| 344.84 | 3.40 | 3.40 |
| 368.82 | 4.57 | 4.57 |
| 372.35 | 4.93 | 4.93 |
| 317.39 | 4.20 | 4.20 |
| 373.24 | 5.22 | 5.22 |
| 318.38 | 4.22 | 4.22 |
| 438.96 | 6.53 | 6.53 |
| 352.82 | 4.87 | 4.87 |
| 356.78 | 4.71 | 4.71 |
| 322.34 | 4.05 | 4.05 |
| 410.90 | 5.31 | 5.31 |
| 304.35 | 3.91 | 3.91 |
| 438.96 | 6.09 | 6.09 |
| 329.36 | 3.78 | 3.78 |
| 309.41 | 4.33 | 4.33 |
| 356.78 | 4.71 | 4.71 |
| 412.87 | 4.59 | 4.59 |
| 332.40 | 4.48 | 4.48 |
| 364.40 | 3.93 | 3.93 |
| 452.98 | 6.92 | 6.92 |
| 424.93 | 5.70 | 5.70 |
| 373.24 | 5.22 | 5.22 |
| 356.78 | 4.71 | 4.71 |
| 338.79 | 4.57 | 4.57 |
| 336.37 | 4.36 | 4.36 |
| 332.40 | 4.53 | 4.53 |
| 352.82 | 4.87 | 4.87 |
| 322.34 | 4.05 | 4.05 |
| 329.36 | 3.78 | 3.78 |
| 307.35 | 3.79 | 3.79 |
| 338.79 | 4.57 | 4.57 |