Assay Report Card

Basic Information

ID: ALA4413245

Type: Binding

Description: Inhibition of PDK1 in human NCI-H1975 cells assessed as switch of pyruvate metabolism from lactate production to oxidative phosphorylation by measuring increase in ROS production at high concentration after 4 hrs by DCFH-DA dye based assay

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
354.443.523.52