Assay Report Card

Basic Information

ID: ALA4413395

Type: Binding

Description: Effect on TCR signaling in OKT3-induced human T-cells harboring SiRNA assessed as restoration of restimulation-induced cell death at 1 to 10 uM preincubated for 30 mins followed by OKT3 stimulation and measured 24 hrs post dose by propidium iodide staining based flow cytometry

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
395.432.422.42
477.585.485.48
365.433.023.02
392.482.932.93