Basic Information
ID: ALA4413397
Type: Binding
Description: Inhibition of DGKalpha in OKT3-induced human T cells harboring SAP SiRNA assessed as restoration of restimulation-induced cell death at 1 to 10 uM preincubated for 30 mins followed by OKT3 stimulation and measured 24 hrs post dose by propidium iodide staining based flow cytometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4413397
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.43 | 2.42 | 2.42 |
| 477.58 | 5.48 | 5.48 |
| 365.43 | 3.02 | 3.02 |