Basic Information
ID: ALA4413482
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as parent compound remaining at 0.2 mM after 30 mins in presence of NADPH by HPLC-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4413482
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.38 | 3.27 | 3.27 |
| 294.35 | 3.09 | 3.09 |
| 284.36 | 2.92 | 2.92 |
| 311.43 | 3.22 | 3.22 |
| 283.37 | 3.53 | 3.53 |
| 336.82 | 3.87 | 3.87 |
| 312.41 | 3.70 | 3.70 |
| 325.46 | 3.61 | 3.61 |
| 366.49 | 3.46 | 3.46 |
| 304.42 | 2.11 | 2.11 |
| 371.27 | 4.60 | 4.60 |
| 334.39 | 3.74 | 3.74 |
| 297.40 | 2.83 | 2.83 |
| 256.30 | 2.14 | 2.14 |
| 270.33 | 2.61 | 2.61 |
| 303.79 | 3.87 | 3.87 |
| 287.33 | 3.36 | 3.36 |
| 316.40 | 3.60 | 3.60 |
| 377.47 | 3.02 | 3.02 |
| 350.85 | 4.26 | 4.26 |
| 360.46 | 4.14 | 4.14 |
| 270.33 | 2.53 | 2.53 |
| 292.34 | 2.81 | 2.81 |
| 270.33 | 2.53 | 2.53 |
| 346.43 | 4.10 | 4.10 |
| 373.50 | 4.58 | 4.58 |
| 296.37 | 2.92 | 2.92 |
| 270.33 | 2.53 | 2.53 |
| 346.43 | 3.61 | 3.61 |
| 346.43 | 3.61 | 3.61 |
| 282.39 | 3.09 | 3.09 |
| 382.49 | 3.16 | 3.16 |