Basic Information
ID: ALA4413538
Type: Binding
Description: Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) at 500 nM using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase mTOR(ALA2842)
Document: ALA4411315
Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) at 500 nM using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4413538
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.38 | -1.00 | -1.00 |
| 454.53 | 2.79 | 2.79 |
| 419.49 | 0.57 | 0.57 |
| 455.52 | 2.19 | 2.19 |
| 405.46 | 0.18 | 0.18 |
| 391.43 | -0.21 | -0.21 |
| 446.56 | 0.87 | 0.87 |
| 432.53 | 0.48 | 0.48 |
| 502.60 | 2.19 | 2.19 |
| 440.51 | 1.76 | 1.76 |
| 430.53 | 2.85 | 2.85 |
| 433.51 | 0.96 | 0.96 |
| 413.48 | 2.11 | 2.11 |
| 414.47 | 2.38 | 2.38 |
| 447.54 | 1.35 | 1.35 |
| 439.52 | 2.37 | 2.37 |
| 465.51 | 1.07 | 1.07 |
| 377.41 | -0.60 | -0.60 |
| 425.49 | 2.18 | 2.18 |
| 441.50 | 1.16 | 1.16 |