Assay Report Card

Basic Information

ID: ALA4413798

Type: Binding

Description: Inhibition of APE1 in human ST8814 cells assessed as effect on MMS-induced DNA damage by measuring tail DNA level at 100 uM after 1 hr in presence of MMS by comet assay (Rvb = 16%)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
371.534.754.75
601.733.503.50
705.885.505.50
691.855.555.55
745.826.266.26
602.665.925.92
630.774.714.71