Basic Information
ID: ALA4413913
Type: Binding
Description: Inhibition of human BRAF V600E mutant using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P-ATP] by scintillation counting method
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase B-raf(ALA5145)
Document: ALA4411323
Inhibition of human BRAF V600E mutant using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P-ATP] by scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4413913
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 520.95 | 5.01 | 5.01 |
| 631.96 | 8.94 | 8.94 |
| 584.39 | 8.28 | 8.28 |
| 616.95 | 8.55 | 8.55 |
| 598.41 | 8.58 | 8.58 |
| 549.85 | 7.82 | 7.82 |
| 602.92 | 8.25 | 8.25 |
| 481.94 | 6.60 | 6.60 |
| 620.03 | 7.07 | 7.07 |
| 550.83 | 7.91 | 7.91 |
| 549.94 | 7.62 | 7.62 |
| 548.95 | 7.53 | 7.53 |
| 563.97 | 7.93 | 7.93 |
| 617.94 | 8.64 | 8.64 |
| 480.96 | 6.52 | 6.52 |
| 534.93 | 7.23 | 7.23 |
| 466.93 | 6.21 | 6.21 |
| 634.06 | 7.37 | 7.37 |
| 535.82 | 7.52 | 7.52 |
| 495.97 | 6.91 | 6.91 |
| 564.86 | 8.21 | 8.21 |