Stability in human liver microsomes assessed as parent compound remaining at 0.1 uM preincubated with MgCl2 for 10 mins followed by NADPH addition mea...

Basic Information

ID: ALA4413956

Type: ADME

Description: Stability in human liver microsomes assessed as parent compound remaining at 0.1 uM preincubated with MgCl2 for 10 mins followed by NADPH addition measured after 60 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA4411327

Stability in human liver microsomes assessed as parent compound remaining at 0.1 uM preincubated with MgCl2 for 10 mins followed by NADPH addition measured after 60 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
659.603.213.21
629.582.772.77