Basic Information
ID: ALA4414022
Type: Binding
Description: Inhibition of SHP2 in human KYSE520 cells assessed as reduction in ERK phosphorylation after 2 hrs by SureFire p-ERK assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4414022
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.27 | 3.35 | 3.35 |
| 382.30 | 2.65 | 2.65 |
| 451.00 | 2.20 | 2.20 |
| 441.48 | 2.67 | 2.67 |
| 454.52 | 3.28 | 3.28 |
| 407.31 | 2.95 | 2.95 |
| 470.52 | 2.26 | 2.26 |
| 399.44 | 2.90 | 2.90 |
| 455.51 | 2.68 | 2.68 |
| 428.39 | 3.39 | 3.39 |
| 486.54 | 3.22 | 3.22 |
| 469.53 | 2.87 | 2.87 |
| 470.43 | 3.15 | 3.15 |
| 477.03 | 2.77 | 2.77 |
| 468.55 | 3.27 | 3.27 |