Basic Information
ID: ALA4414032
Type: Functional
Description: In vivo inhibition of SHP2 in human KYSE520 cells xenografted in NU/NU mouse assessed as reduction in phosphorylated ERK levels at 100 mg/kg, po administered as single dose after 3 hrs
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4414032
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.43 | 3.15 | 3.15 |