Basic Information
ID: ALA4414121
Type: Binding
Description: Inhibition of human 6His-tagged SHP2 (1 to 525 residues) expressed in Escherichia coli BL21 Star (DE3) using DiFMUP as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA4411333
Inhibition of human 6His-tagged SHP2 (1 to 525 residues) expressed in Escherichia coli BL21 Star (DE3) using DiFMUP as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414121
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.95 | 1.75 | 1.75 |
| 447.37 | 3.73 | 3.73 |
| 484.99 | 2.28 | 2.28 |
| 499.02 | 2.67 | 2.67 |
| 395.47 | 1.05 | 1.05 |
| 463.37 | 2.96 | 2.96 |
| 449.34 | 2.57 | 2.57 |
| 464.36 | 2.36 | 2.36 |
| 407.31 | 2.95 | 2.95 |
| 424.51 | 0.94 | 0.94 |
| 433.34 | 3.66 | 3.66 |
| 432.36 | 4.26 | 4.26 |
| 311.20 | 4.00 | 4.00 |
| 421.33 | 3.20 | 3.20 |
| 444.93 | 1.29 | 1.29 |
| 476.99 | 1.77 | 1.77 |