Basic Information
ID: ALA4414122
Type: Binding
Description: Inhibition of of SHP2 in human KYSE520 cells assessed as suppression of ERK phosphorylation after 2 hrs by AlphaScreen SureFire Phospho-ERK1/2 assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA4411333
Inhibition of of SHP2 in human KYSE520 cells assessed as suppression of ERK phosphorylation after 2 hrs by AlphaScreen SureFire Phospho-ERK1/2 assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414122
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.95 | 1.75 | 1.75 |
| 447.37 | 3.73 | 3.73 |
| 484.99 | 2.28 | 2.28 |
| 499.02 | 2.67 | 2.67 |
| 395.47 | 1.05 | 1.05 |
| 463.37 | 2.96 | 2.96 |
| 449.34 | 2.57 | 2.57 |
| 464.36 | 2.36 | 2.36 |
| 407.31 | 2.95 | 2.95 |
| 424.51 | 0.94 | 0.94 |
| 433.34 | 3.66 | 3.66 |
| 432.36 | 4.26 | 4.26 |
| 421.33 | 3.20 | 3.20 |
| 444.93 | 1.29 | 1.29 |
| 476.99 | 1.77 | 1.77 |