Basic Information
ID: ALA4414135
Type: Binding
Description: Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluorescence polarization binding assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase ABL(ALA1862)
Document: ALA4411335
Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluorescence polarization binding assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414135
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.33 | 2.56 | 2.56 |
| 303.21 | 3.59 | 3.59 |
| 252.73 | 3.42 | 3.42 |
| 311.17 | 2.94 | 2.94 |
| 234.28 | 2.47 | 2.47 |
| 286.16 | 2.90 | 2.90 |
| 335.19 | 3.34 | 3.34 |
| 297.14 | 2.55 | 2.55 |
| 350.21 | 3.05 | 3.05 |
| 350.21 | 2.98 | 2.98 |
| 385.22 | 5.65 | 5.65 |
| 343.21 | 2.16 | 2.16 |
| 323.23 | 3.49 | 3.49 |
| 353.18 | 3.48 | 3.48 |
| 336.18 | 2.74 | 2.74 |
| 230.10 | 2.48 | 2.48 |
| 355.23 | 2.30 | 2.30 |
| 400.32 | 3.98 | 3.98 |
| 398.23 | 4.01 | 4.01 |
| 311.19 | 4.57 | 4.57 |
| 311.19 | 4.57 | 4.57 |
| 379.25 | 2.95 | 2.95 |
| 286.16 | 2.90 | 2.90 |
| 286.16 | 3.04 | 3.04 |
| 313.21 | 4.47 | 4.47 |
| 370.19 | 4.23 | 4.23 |
| 293.20 | 4.14 | 4.14 |
| 270.72 | 3.56 | 3.56 |
| 287.17 | 4.08 | 4.08 |
| 272.13 | 2.65 | 2.65 |
| 252.73 | 3.42 | 3.42 |
| 335.19 | 3.34 | 3.34 |
| 313.17 | 3.36 | 3.36 |
| 286.16 | 3.04 | 3.04 |
| 353.18 | 3.48 | 3.48 |
| 270.72 | 3.56 | 3.56 |
| 350.23 | 4.76 | 4.76 |
| 224.25 | 1.46 | 1.46 |
| 356.26 | 4.83 | 4.83 |
| 295.13 | 3.24 | 3.24 |
| 335.19 | 3.34 | 3.34 |
| 379.25 | 2.95 | 2.95 |
| 306.15 | 3.91 | 3.91 |
| 286.16 | 2.90 | 2.90 |
| 266.75 | 3.73 | 3.73 |
| 312.18 | 3.97 | 3.97 |
| 312.18 | 3.97 | 3.97 |
| 336.18 | 2.74 | 2.74 |
| 313.17 | 3.36 | 3.36 |
| 336.18 | 2.74 | 2.74 |
| 336.18 | 2.74 | 2.74 |
| 295.13 | 3.03 | 3.03 |