Basic Information
ID: ALA4414204
Type: Binding
Description: Ratio of I50 for inhibition of CK2alpha in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysis to IC50 for inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Casein kinase II alpha(ALA3629)
Document: ALA4411336
Ratio of I50 for inhibition of CK2alpha in human 786-0 cells assessed as decrease in Akt1 phosphorylation at Ser129 after 24 hrs by Western blot analysis to IC50 for inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414204
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.66 | 5.04 | 5.04 |
| 362.41 | 5.11 | 5.11 |