Basic Information
ID: ALA4414347
Type: ADME
Description: Metabolic stability in Sprague-Dawley rat liver microsomes assessed as remaining parent compound level at 10 uM preincubated for 5 mins with NADPH generating system followed by liver microsomes addition and measured after 60 mins by HPLC analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4414347
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.81 | 3.67 | 3.67 |
| 379.91 | 5.23 | 5.23 |
| 381.35 | 3.61 | 3.61 |
| 349.84 | 3.93 | 3.93 |