Assay Report Card

Basic Information

ID: ALA4414356

Type: ADME

Description: Activation of LXR in human HepG2 cells assessed as increase in SREBP-1c mRNA expression at 1 uM after 12 hrs followed by renewal of medium containing test compounds after 6 hrs by PCR analysis

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
348.496.106.10
381.353.613.61