Basic Information
ID: ALA4414744
Type: Binding
Description: Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation at 1 uM preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4414547
Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation at 1 uM preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414744
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 284.31 | 2.90 | 2.90 |
| 284.31 | 2.90 | 2.90 |
| 268.31 | 3.31 | 3.31 |
| 284.31 | 2.90 | 2.90 |