Basic Information
ID: ALA4414747
Type: Binding
Description: Potency index, ratio of CAPE IC50 to compound IC50 for inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4414547
Potency index, ratio of CAPE IC50 to compound IC50 for inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414747
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.31 | 2.90 | 2.90 |
| 268.31 | 3.31 | 3.31 |