Basic Information
ID: ALA4414772
Type: Binding
Description: Inhibition of human 5-LO transfected in HEK293 cells coexpressing FLAP assessed as leukotriene formation at 1 uM using arachidonic acid as substrate preincubated for 5 mins followed by calcium ionophore A23187/arachidonic acid addition and measured after 15 mins by RP-HPLC analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4414547
Inhibition of human 5-LO transfected in HEK293 cells coexpressing FLAP assessed as leukotriene formation at 1 uM using arachidonic acid as substrate preincubated for 5 mins followed by calcium ionophore A23187/arachidonic acid addition and measured after 15 mins by RP-HPLC analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4414772
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.31 | 2.90 | 2.90 |
| 284.31 | 2.90 | 2.90 |
| 284.31 | 2.90 | 2.90 |