Basic Information
ID: ALA4414794
Type: Binding
Description: Inhibition of [3H]cAMP binding to recombinant human His-Tb fused PDE4D2 (86 to 413 residues) expressed in Escherichia coli using [3H]cAMP as substrate preincubated for 10 mins followed by [3H]cAMP addition and measured after 1 hr by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4414794
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.48 | 3.26 | 3.26 |
| 367.38 | 3.47 | 3.47 |
| 383.45 | 4.18 | 4.18 |
| 403.36 | 3.75 | 3.75 |
| 415.45 | 2.87 | 2.87 |
| 380.38 | 2.56 | 2.56 |
| 337.36 | 3.46 | 3.46 |