Basic Information
ID: ALA4414800
Type: Binding
Description: Inhibition of TYK2 JH2 domain in mouse whole blood assessed as inhibition of IFNalpha-induced STAT1 phosphorylation preincubated for 1 hr followed by IFNalpha stimulation and measured after 15 mins by fluorescence assay
Organism: Mus musculus
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4414800
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.45 | 1.94 | 1.94 |
| 401.47 | 2.12 | 2.12 |
| 418.47 | 2.87 | 2.87 |
| 392.46 | 1.33 | 1.33 |
| 415.45 | 2.87 | 2.87 |
| 401.42 | 2.61 | 2.61 |
| 397.46 | 2.73 | 2.73 |
| 419.46 | 2.26 | 2.26 |