Basic Information
ID: ALA4415075
Type: Functional
Description: Antiviral activity against Dengue virus 1 WestPac infected in human HuH7 replicon cells expressing Renilla luciferase and neomycin-resistance genes assessed as reduction in viral replication incubated for 48 hrs by luciferase reporter replicon-based assay
Format: BAO_0000218
Organism: dengue virus type 1
Strain: WestPac
Target: dengue virus type 1(ALA613360)
Document: ALA4414551
Antiviral activity against Dengue virus 1 WestPac infected in human HuH7 replicon cells expressing Renilla luciferase and neomycin-resistance genes assessed as reduction in viral replication incubated for 48 hrs by luciferase reporter replicon-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4415075
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 548.43 | 5.38 | 5.38 |
| 512.44 | 5.38 | 5.38 |
| 485.38 | 3.39 | 3.39 |
| 468.34 | 4.36 | 4.36 |
| 484.39 | 4.46 | 4.46 |
| 498.41 | 5.22 | 5.22 |
| 539.47 | 4.66 | 4.66 |
| 578.46 | 5.39 | 5.39 |
| 442.31 | 3.80 | 3.80 |
| 480.36 | 4.19 | 4.19 |
| 570.84 | 6.16 | 6.16 |
| 519.39 | 4.76 | 4.76 |
| 428.28 | 3.77 | 3.77 |
| 500.34 | 3.34 | 3.34 |
| 511.41 | 3.87 | 3.87 |
| 470.36 | 4.58 | 4.58 |
| 591.52 | 3.15 | 3.15 |
| 555.47 | 3.89 | 3.89 |
| 553.84 | 5.42 | 5.42 |
| 568.55 | 7.31 | 7.31 |
| 500.39 | 4.21 | 4.21 |
| 554.48 | 3.42 | 3.42 |
| 553.49 | 5.05 | 5.05 |
| 484.39 | 4.97 | 4.97 |
| 536.39 | 5.51 | 5.51 |
| 533.42 | 5.07 | 5.07 |
| 518.83 | 5.19 | 5.19 |
| 527.46 | 4.51 | 4.51 |
| 567.52 | 5.44 | 5.44 |
| 518.40 | 5.37 | 5.37 |
| 525.44 | 4.26 | 4.26 |
| 552.85 | 6.02 | 6.02 |
| 456.33 | 4.19 | 4.19 |
| 583.56 | 6.07 | 6.07 |
| 519.39 | 4.76 | 4.76 |
| 500.39 | 4.21 | 4.21 |
| 482.37 | 4.58 | 4.58 |
| 544.44 | 4.57 | 4.57 |
| 516.39 | 3.79 | 3.79 |
| 474.32 | 4.14 | 4.14 |
| 499.40 | 3.73 | 3.73 |
| 500.34 | 3.34 | 3.34 |
| 513.43 | 4.12 | 4.12 |
| 512.44 | 5.75 | 5.75 |
| 549.26 | 4.95 | 4.95 |
| 512.44 | 5.61 | 5.61 |
| 536.39 | 5.51 | 5.51 |
| 470.36 | 4.58 | 4.58 |
| 532.43 | 5.41 | 5.41 |
| 541.44 | 3.50 | 3.50 |
| 472.33 | 3.16 | 3.16 |
| 555.51 | 5.29 | 5.29 |
| 519.39 | 4.76 | 4.76 |
| 466.33 | 3.80 | 3.80 |
| 484.39 | 4.83 | 4.83 |
| 470.36 | 4.58 | 4.58 |
| 630.62 | 7.96 | 7.96 |
| 611.62 | 6.85 | 6.85 |