Resistance index, ratio of EC50 for antiviral activity against NS3 T606A mutant and NS4B V63M mutant containing Dengue virus 2 isolate P12-III infecte...

Basic Information

ID: ALA4415076

Type: Functional

Description: Resistance index, ratio of EC50 for antiviral activity against NS3 T606A mutant and NS4B V63M mutant containing Dengue virus 2 isolate P12-III infected in human HuH7 cells using viral isolates selected by serial passaging in presence of test compound incubated for 3 days by viral reduction assay to EC50 for antiviral activity against Dengue virus 2 isolate P0 infected in human HuH7 cells incubated for 3 days by viral reduction assay

Format: BAO_0000218

Organism: dengue virus type 2

Target:  dengue virus type 2(ALA613966)

Document:  ALA4414551

Resistance index, ratio of EC50 for antiviral activity against NS3 T606A mutant and NS4B V63M mutant containing Dengue virus 2 isolate P12-III infected in human HuH7 cells using viral isolates selected by serial passaging in presence of test compound incubated for 3 days by viral reduction assay to EC50 for antiviral activity against Dengue virus 2 isolate P0 infected in human HuH7 cells incubated for 3 days by viral reduction assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
499.403.733.73