Basic Information
ID: ALA4415176
Type: Binding
Description: Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response preincubated for 2 hrs followed by SAG addition and measured after 24 hrs by Bright-Glo luciferase assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4415176
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.34 | 3.99 | 3.99 |
| 328.80 | 3.74 | 3.74 |
| 370.28 | 3.74 | 3.74 |
| 330.84 | 3.86 | 3.86 |
| 286.38 | 3.17 | 3.17 |
| 300.75 | 3.70 | 3.70 |
| 355.79 | 4.64 | 4.64 |
| 300.79 | 4.17 | 4.17 |
| 320.82 | 4.08 | 4.08 |
| 422.79 | 4.88 | 4.88 |
| 375.39 | 4.00 | 4.00 |
| 404.72 | 4.39 | 4.39 |
| 328.80 | 3.69 | 3.69 |
| 314.77 | 3.70 | 3.70 |