Basic Information
ID: ALA4415472
Type: ADME
Description: Reversible inhibition of CYP1A2 in human liver microsomes at 10 uM using phenacetin as substrate preincubated for 5 mins followed by NADPH generating system addition and measured after 20 mins relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4415472
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 541.70 | 4.18 | 4.18 |
| 415.54 | 4.67 | 4.67 |
| 499.62 | 2.96 | 2.96 |
| 527.67 | 3.74 | 3.74 |
| 387.49 | 3.88 | 3.88 |