Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation pre-treated with 4 uM VHL1 for 2 hrs followed by ...

Basic Information

ID: ALA4415979

Type: Binding

Description: Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation pre-treated with 4 uM VHL1 for 2 hrs followed by compound addition at 100 nM and further incubated for 8 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: K562

Target:  VHL/BCR-ABL1(ALA4523751)

Document:  ALA4414590

Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation pre-treated with 4 uM VHL1 for 2 hrs followed by compound addition at 100 nM and further incubated for 8 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1012.70