Basic Information
ID: ALA4415980
Type: Binding
Description: Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation pre-treated with 100 nM dasatinib for 2 hrs followed by compound addition at 100 nM and further incubated for 8 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562
Target: VHL/BCR-ABL1(ALA4523751)
Document: ALA4414590
Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation pre-treated with 100 nM dasatinib for 2 hrs followed by compound addition at 100 nM and further incubated for 8 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4415980
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1012.70 |