Basic Information
ID: ALA4415981
Type: Binding
Description: Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation pre-treated with 2.5 uM proteasome inhibitor MG132 for 2 hrs followed by compound addition at 100 nM and further incubated for 8 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4415981
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1012.70 |