Basic Information
ID: ALA4416020
Type: Binding
Description: Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation at 20 times IC50 incubated for 12 hrs followed by drug wash-out and incubation in drug-free medium up to 72 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562
Target: VHL/BCR-ABL1(ALA4523751)
Document: ALA4414590
Protac activity against VHL/BCR-ABL in human K562 cells assessed as induction of BCR-ABL degradation at 20 times IC50 incubated for 12 hrs followed by drug wash-out and incubation in drug-free medium up to 72 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4416020
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.02 | 3.31 | 3.31 |
| 1012.70 | ||
| 1012.70 |