Basic Information
ID: ALA4416111
Type: Binding
Description: Inhibition of GST-tagged human EGFR D770_N771insNPG mutant using poly(Glu, Tyr) 4:1 substrate incubated for 120 mins by kinase-Glo plus luminescent kinase assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4414600
Inhibition of GST-tagged human EGFR D770_N771insNPG mutant using poly(Glu, Tyr) 4:1 substrate incubated for 120 mins by kinase-Glo plus luminescent kinase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4416111
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 491.35 | 5.38 | 5.38 |
| 460.54 | 6.85 | 6.85 |
| 533.63 | 5.76 | 5.76 |
| 492.60 | 6.30 | 6.30 |
| 506.56 | 5.84 | 5.84 |