Basic Information
ID: ALA4416169
Type: Functional
Description: Antiplasmodial activity against Plasmodium falciparum 3D7A erythrocytic stage assessed as reduction in [3H]hypoxanthine incorporation preincubated for 24 hrs followed by [3H]hypoxanthine addition and measured after 24 hrs by microbeta scintillation counting method
Organism: Plasmodium falciparum
Strain: 3D7A
Activity Charts
Bioactivity
Activity Types for Assay ALA4416169
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.72 | 2.52 | 2.52 |
| 384.43 | 2.60 | 2.60 |
| 516.67 | 4.41 | 4.41 |
| 529.69 | 5.37 | 5.37 |
| 476.58 | 4.41 | 4.41 |
| 478.64 | 4.55 | 4.55 |
| 447.54 | 4.72 | 4.72 |
| 426.57 | 3.85 | 3.85 |
| 466.63 | 4.63 | 4.63 |
| 453.57 | 4.78 | 4.78 |
| 522.69 | 4.42 | 4.42 |
| 433.52 | 4.41 | 4.41 |
| 432.53 | 5.01 | 5.01 |
| 452.60 | 4.38 | 4.38 |
| 492.60 | 6.02 | 6.02 |
| 489.58 | 4.52 | 4.52 |
| 392.53 | 4.39 | 4.39 |
| 413.52 | 3.93 | 3.93 |
| 501.64 | 5.16 | 5.16 |
| 447.54 | 4.14 | 4.14 |
| 572.71 | 4.84 | 4.84 |
| 553.69 | 4.71 | 4.71 |
| 379.49 | 3.48 | 3.48 |
| 504.61 | 6.34 | 6.34 |
| 484.67 | 4.33 | 4.33 |
| 448.53 | 4.57 | 4.57 |
| 601.75 | 6.24 | 6.24 |
| 438.58 | 3.99 | 3.99 |
| 449.56 | 4.66 | 4.66 |
| 409.53 | 4.47 | 4.47 |
| 460.58 | 5.63 | 5.63 |
| 477.57 | 4.81 | 4.81 |
| 417.45 | 3.94 | 3.94 |
| 476.58 | 5.33 | 5.33 |
| 448.53 | 4.72 | 4.72 |
| 481.65 | 3.53 | 3.53 |
| 529.69 | 5.37 | 5.37 |
| 517.63 | 4.40 | 4.40 |
| 594.74 | 4.05 | 4.05 |
| 399.50 | 3.28 | 3.28 |
| 425.53 | 3.44 | 3.44 |
| 433.52 | 4.41 | 4.41 |
| 518.64 | 6.73 | 6.73 |
| 508.67 | 4.17 | 4.17 |
| 453.59 | 4.59 | 4.59 |
| 439.56 | 4.46 | 4.46 |
| 449.63 | 4.50 | 4.50 |
| 439.55 | 4.47 | 4.47 |
| 515.62 | 4.91 | 4.91 |
| 433.52 | 4.41 | 4.41 |
| 468.60 | 3.62 | 3.62 |
| 436.52 | 4.91 | 4.91 |
| 504.64 | 4.74 | 4.74 |
| 464.55 | 5.46 | 5.46 |
| 461.57 | 4.48 | 4.48 |
| 355.44 | 3.46 | 3.46 |
| 446.56 | 4.88 | 4.88 |
| 446.56 | 5.32 | 5.32 |
| 452.58 | 5.38 | 5.38 |