Basic Information
ID: ALA4416194
Type: Functional
Description: Antiplasmodial activity against Plasmodium falciparum 3D7A harboring with PKG T618Q mutant asexual erythrocytic stage assessed as reduction in [3H]hypoxanthine incorporation preincubated for 72 hrs followed by [3H]hypoxanthine addition and measured after 24 hrs by microbeta scintillation counting method
Organism: Plasmodium falciparum
Strain: 3D7A
Activity Charts
Bioactivity
Activity Types for Assay ALA4416194
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.67 | 4.41 | 4.41 |
| 433.52 | 4.41 | 4.41 |
| 460.58 | 5.63 | 5.63 |
| 433.52 | 4.41 | 4.41 |
| 446.56 | 5.32 | 5.32 |