Basic Information
ID: ALA4416278
Type: Functional
Description: Antagonist activity at SNAP-tagged human D2LR expressed in Flp-In CHO cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP accumulation at 10 uM preincubated with compound followed by forskolin and dopamine addition and measured after 10 mins by BRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4416278
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.87 | 4.43 | 4.43 |
| 341.43 | 3.77 | 3.77 |
| 325.43 | 4.67 | 4.67 |
| 377.89 | 4.28 | 4.28 |
| 361.84 | 4.04 | 4.04 |
| 359.87 | 5.32 | 5.32 |
| 389.90 | 5.08 | 5.08 |
| 392.33 | 4.94 | 4.94 |
| 357.88 | 4.29 | 4.29 |
| 360.86 | 4.26 | 4.26 |
| 375.87 | 4.43 | 4.43 |
| 361.89 | 4.79 | 4.79 |
| 379.93 | 4.94 | 4.94 |
| 363.86 | 4.23 | 4.23 |
| 355.45 | 4.08 | 4.08 |
| 357.86 | 5.23 | 5.23 |
| 410.32 | 5.08 | 5.08 |
| 409.42 | 4.79 | 4.79 |
| 359.87 | 4.87 | 4.87 |
| 410.32 | 5.08 | 5.08 |
| 323.44 | 3.63 | 3.63 |
| 389.90 | 4.82 | 4.82 |
| 401.91 | 4.96 | 4.96 |
| 410.32 | 5.08 | 5.08 |
| 375.87 | 4.43 | 4.43 |
| 359.42 | 3.91 | 3.91 |
| 393.86 | 4.56 | 4.56 |
| 393.86 | 4.56 | 4.56 |
| 393.86 | 4.56 | 4.56 |
| 371.88 | 4.59 | 4.59 |
| 451.97 | 6.09 | 6.09 |
| 373.90 | 4.96 | 4.96 |
| 392.33 | 4.94 | 4.94 |
| 359.87 | 4.87 | 4.87 |
| 357.86 | 4.20 | 4.20 |
| 371.91 | 4.59 | 4.59 |
| 393.86 | 4.56 | 4.56 |
| 375.87 | 4.43 | 4.43 |
| 375.92 | 5.18 | 5.18 |
| 371.88 | 5.11 | 5.11 |
| 410.32 | 5.08 | 5.08 |
| 373.90 | 4.96 | 4.96 |
| 375.87 | 4.43 | 4.43 |
| 410.32 | 5.08 | 5.08 |
| 375.87 | 4.43 | 4.43 |
| 384.50 | 3.84 | 3.84 |
| 410.32 | 5.08 | 5.08 |
| 393.86 | 4.56 | 4.56 |
| 347.86 | 4.40 | 4.40 |
| 343.83 | 3.81 | 3.81 |
| 393.86 | 4.56 | 4.56 |