Basic Information
ID: ALA4416333
Type: Binding
Description: Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium level using quinoline as substrate in presence of SAM and measured every 27 seconds for 5.5 mins by fluorescence-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4416333
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.57 | -1.14 | -1.14 |
| 514.54 | -1.53 | -1.53 |
| 366.38 | -1.00 | -1.00 |
| 553.53 | -0.89 | -0.89 |
| 513.56 | -0.04 | -0.04 |
| 509.52 | -0.62 | -0.62 |
| 513.56 | -0.04 | -0.04 |
| 406.44 | -0.57 | -0.57 |
| 494.51 | 0.44 | 0.44 |
| 577.52 | 0.40 | 0.40 |
| 545.58 | -1.07 | -1.07 |
| 527.51 | -0.48 | -0.48 |
| 510.51 | -1.23 | -1.23 |
| 535.56 | -0.44 | -0.44 |
| 390.40 | -1.14 | -1.14 |
| 494.51 | -0.76 | -0.76 |
| 510.51 | -1.23 | -1.23 |
| 466.50 | 0.28 | 0.28 |
| 493.52 | -0.16 | -0.16 |
| 408.42 | -0.04 | -0.04 |
| 509.52 | -0.62 | -0.62 |
| 523.55 | -0.31 | -0.31 |
| 500.52 | -1.57 | -1.57 |
| 521.53 | -0.48 | -0.48 |
| 420.43 | -0.19 | -0.19 |
| 543.97 | 0.03 | 0.03 |
| 465.51 | -0.08 | -0.08 |
| 509.52 | -0.62 | -0.62 |
| 523.55 | -0.53 | -0.53 |
| 508.54 | -1.22 | -1.22 |
| 531.57 | 1.01 | 1.01 |
| 523.55 | -0.23 | -0.23 |
| 510.51 | -1.23 | -1.23 |
| 510.51 | -1.23 | -1.23 |
| 509.52 | -0.62 | -0.62 |