Assay Report Card

Basic Information

ID: ALA4416341

Type: ADME

Description: Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level at 1 uM using 6-mercaptopurine as substrate in presence of SAM incubated for 30 mins by LC-MS/MS analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
509.52-0.62-0.62