Basic Information
ID: ALA4416351
Type: ADME
Description: Inhibition of human DOT1L expressed in Escherichia coli assessed as reduction in methylated polynucleosome level using polynucleosome as substrate in presence of [3H] SAM incubated for 15 mins by scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4416351
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.52 | -0.62 | -0.62 |