Basic Information
ID: ALA4416387
Type: Functional
Description: Ratio of IC50 for allosteric modulator activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgammaS binding incubated for 60 mins by scintillation counting method IC50 for allosteric modulator activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of 1 uM CP55,940-induced [35S]GTPgammaS binding incubated for 60 mins by scintillation counting method
Format: BAO_0000219
Organism: Homo sapiens
Target: Cannabinoid CB1 receptor(ALA218)
Document: ALA4414612
Ratio of IC50 for allosteric modulator activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgammaS binding incubated for 60 mins by scintillation counting method IC50 for allosteric modulator activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of 1 uM CP55,940-induced [35S]GTPgammaS binding incubated for 60 mins by scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4416387
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.89 | 5.65 | 5.65 |
| 371.89 | 5.78 | 5.78 |
| 346.81 | 5.85 | 5.85 |
| 363.27 | 6.37 | 6.37 |
| 397.71 | 7.02 | 7.02 |
| 358.85 | 5.72 | 5.72 |
| 329.81 | 5.11 | 5.11 |
| 358.85 | 5.72 | 5.72 |
| 364.80 | 5.99 | 5.99 |