Inhibition of JAK1/3 in human Ramos cells harboring beta-lactamase reporter gene assessed as reduction in IL4-induced STAT6 phosphorylation incubated ...

Basic Information

ID: ALA4416477

Type: Binding

Description: Inhibition of JAK1/3 in human Ramos cells harboring beta-lactamase reporter gene assessed as reduction in IL4-induced STAT6 phosphorylation incubated for 2 hrs by FRET assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Ramos

Target: JAK3/JAK1(ALA3038491)

Document: ALA4414617

Inhibition of JAK1/3 in human Ramos cells harboring beta-lactamase reporter gene assessed as reduction in IL4-induced STAT6 phosphorylation incubated for 2 hrs by FRET assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4416477

IC50

Total(16)

Parent Molecular Weight	ALogP	Polar Surface Area
428.84	1.28	1.28
367.34	1.69	1.69
401.79	2.35	2.35
365.40	2.20	2.20
354.35	1.92	1.92
361.37	1.66	1.66
428.81	2.72	2.72
385.33	1.83	1.83
424.39	2.07	2.07
399.84	2.85	2.85
412.36	2.20	2.20
408.39	2.37	2.37
394.40	0.63	0.63
390.40	1.97	1.97
394.37	2.06	2.06
394.40	0.63	0.63

Parent Molecular Weight

ALogP

Polar Surface Area

428.84

1.28

367.34

1.69

401.79

2.35

365.40

2.20

354.35

1.92

361.37

1.66

428.81

2.72

385.33

1.83

424.39

2.07

399.84

2.85

412.36

2.20

408.39

2.37

394.40

0.63

390.40

1.97

394.37

2.06

394.40

0.63

Inhibition of JAK1/3 in human Ramos cells harboring beta-lactamase reporter gene assessed as reduction in IL4-induced STAT6 phosphorylation incubated ...

Basic Information

Activity Charts

Compound Summary