Basic Information
ID: ALA4416547
Type: Functional
Description: Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay
Organism: Rattus norvegicus
Cell type: RBL-2H3
Activity Charts
Bioactivity
Activity Types for Assay ALA4416547
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.47 | 6.11 | 6.11 |
| 278.44 | 5.66 | 5.66 |
| 280.45 | 5.88 | 5.88 |
| 325.54 | 5.13 | 5.13 |
| 347.54 | 5.24 | 5.24 |
| 304.47 | 6.22 | 6.22 |
| 501.67 | 5.51 | 5.51 |
| 349.56 | 5.46 | 5.46 |
| 463.66 | 7.23 | 7.23 |
| 323.52 | 4.91 | 4.91 |
| 328.50 | 6.55 | 6.55 |
| 302.46 | 5.99 | 5.99 |
| 306.49 | 6.44 | 6.44 |
| 321.51 | 4.68 | 4.68 |
| 338.58 | 7.67 | 7.67 |
| 385.55 | 5.67 | 5.67 |
| 371.57 | 5.57 | 5.57 |
| 381.65 | 6.69 | 6.69 |
| 401.59 | 4.93 | 4.93 |
| 401.59 | 4.93 | 4.93 |
| 345.53 | 5.02 | 5.02 |
| 336.56 | 7.44 | 7.44 |
| 372.55 | 6.00 | 6.00 |
| 512.67 | 6.88 | 6.88 |
| 410.65 | 6.24 | 6.24 |
| 385.59 | 5.96 | 5.96 |
| 419.61 | 7.81 | 7.81 |
| 385.59 | 5.96 | 5.96 |
| 379.63 | 6.47 | 6.47 |
| 535.67 | 7.99 | 7.99 |
| 383.62 | 7.38 | 7.38 |
| 483.67 | 6.68 | 6.68 |
| 385.59 | 5.96 | 5.96 |
| 385.59 | 5.92 | 5.92 |
| 370.58 | 5.54 | 5.54 |
| 481.70 | 7.28 | 7.28 |
| 474.71 | 5.57 | 5.57 |
| 405.60 | 5.54 | 5.54 |
| 415.62 | 5.59 | 5.59 |
| 416.60 | 6.02 | 6.02 |
| 431.64 | 6.07 | 6.07 |
| 473.70 | 7.03 | 7.03 |
| 399.62 | 6.57 | 6.57 |
| 447.69 | 6.71 | 6.71 |
| 502.12 | 7.62 | 7.62 |
| 369.59 | 6.99 | 6.99 |
| 369.59 | 6.99 | 6.99 |
| 509.58 | 7.07 | 7.07 |
| 467.68 | 6.97 | 6.97 |
| 397.60 | 6.32 | 6.32 |
| 411.63 | 6.76 | 6.76 |
| 481.70 | 7.11 | 7.11 |
| 551.67 | 7.87 | 7.87 |
| 459.57 | 6.43 | 6.43 |
| 425.66 | 7.01 | 7.01 |
| 511.68 | 6.67 | 6.67 |
| 419.61 | 7.81 | 7.81 |
| 385.59 | 6.23 | 6.23 |
| 399.58 | 5.75 | 5.75 |
| 525.71 | 6.76 | 6.76 |
| 415.62 | 5.28 | 5.28 |
| 402.58 | 5.36 | 5.36 |
| 485.67 | 7.11 | 7.11 |