Basic Information
ID: ALA4416548
Type: Functional
Description: Antiallergic activity in BALB/c mouse assessed as reduction in anti-DNP-IgE-mediated passive cutaneous anaphylaxis at 1000 mg/kg, po administered once daily for 5 days followed by anti-DNP-IgE stimulation on day 4 and subsequent DNP-HSA challenge on day 5 post 1 hr compound dose and measured after 30 mins by Evans blue dye-based spectrophotometric method relative to control
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA4416548
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 328.50 | 6.55 | 6.55 |
| 321.51 | 4.68 | 4.68 |
| 385.55 | 5.67 | 5.67 |
| 371.57 | 5.57 | 5.57 |
| 401.59 | 4.93 | 4.93 |
| 401.59 | 4.93 | 4.93 |
| 512.67 | 6.88 | 6.88 |
| 385.59 | 5.96 | 5.96 |
| 535.67 | 7.99 | 7.99 |
| 385.59 | 5.96 | 5.96 |
| 415.62 | 5.59 | 5.59 |
| 447.69 | 6.71 | 6.71 |
| 481.70 | 7.11 | 7.11 |
| 551.67 | 7.87 | 7.87 |
| 485.67 | 7.11 | 7.11 |