Basic Information
ID: ALA4416609
Type: Binding
Description: Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs before compound addition with ATP for 30 mins by ELISA
Format: BAO_0000357
Organism: Mus musculus
Target: NACHT, LRR and PYD domains-containing protein 3(ALA3779755)
Document: ALA4414625
Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5 hrs before compound addition with ATP for 30 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4416609
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.49 | 2.99 | 2.99 |
| 446.96 | 3.02 | 3.02 |
| 545.13 | 4.92 | 4.92 |