Basic Information
ID: ALA4416772
Type: Binding
Description: Antagonist activity at alpha4beta2 nAChR (unknown origin) transfected in HEK cells assessed as decrease in ACh-induced intracellular calcium release incubated for 30 mins by FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor; alpha4/beta2(ALA1907589)
Document: ALA4414639
Antagonist activity at alpha4beta2 nAChR (unknown origin) transfected in HEK cells assessed as decrease in ACh-induced intracellular calcium release incubated for 30 mins by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4416772
Ka
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.45 | 5.22 | 5.22 |
| 416.46 | 3.87 | 3.87 |
| 414.54 | 4.44 | 4.44 |
| 397.48 | 4.34 | 4.34 |
| 429.55 | 4.87 | 4.87 |
| 383.45 | 4.15 | 4.15 |
| 359.46 | 4.20 | 4.20 |
| 402.89 | 4.38 | 4.38 |
| 428.50 | 3.74 | 3.74 |
| 398.47 | 3.73 | 3.73 |
| 374.47 | 3.78 | 3.78 |
| 428.50 | 3.74 | 3.74 |
| 401.45 | 4.29 | 4.29 |
| 440.55 | 4.76 | 4.76 |
| 445.55 | 3.89 | 3.89 |
| 461.55 | 3.55 | 3.55 |
| 416.46 | 3.87 | 3.87 |
| 362.44 | 2.31 | 2.31 |
| 426.52 | 4.51 | 4.51 |
| 399.46 | 3.13 | 3.13 |
| 451.45 | 5.17 | 5.17 |
| 405.55 | 4.92 | 4.92 |
| 371.42 | 4.28 | 4.28 |