Basic Information
ID: ALA4416776
Type: Binding
Description: Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at 30 uM at -60 mV holding potential followed washout for 181 sec and then 60 uM of Ach was applied by two electrode voltage clamp assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA4414639
Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at 30 uM at -60 mV holding potential followed washout for 181 sec and then 60 uM of Ach was applied by two electrode voltage clamp assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4416776
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.46 | 3.87 | 3.87 |
| 383.45 | 4.15 | 4.15 |
| 398.47 | 3.73 | 3.73 |
| 401.45 | 4.29 | 4.29 |