Basic Information
ID: ALA4416947
Type: Binding
Description: Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound followed by Fluor de Lys deacetylase substrate addition by fluorescence method
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4416947
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 137.14 | 0.81 | 0.81 |
| 152.15 | 0.39 | 0.39 |
| 421.50 | 4.55 | 4.55 |
| 335.41 | 2.80 | 2.80 |
| 341.41 | 3.64 | 3.64 |
| 433.51 | 4.13 | 4.13 |
| 270.29 | 1.70 | 1.70 |
| 217.23 | 1.05 | 1.05 |
| 314.34 | 1.37 | 1.37 |
| 484.53 | 2.19 | 2.19 |
| 312.35 | 3.07 | 3.07 |
| 308.34 | 2.19 | 2.19 |
| 382.33 | 2.33 | 2.33 |
| 218.22 | 0.51 | 0.51 |
| 332.27 | 1.18 | 1.18 |
| 295.30 | 2.45 | 2.45 |
| 368.39 | 3.09 | 3.09 |
| 301.33 | 1.57 | 1.57 |
| 194.19 | 0.76 | 0.76 |
| 297.28 | 0.30 | 0.30 |
| 462.56 | 1.96 | 1.96 |
| 421.35 | 4.16 | 4.16 |
| 416.36 | 2.35 | 2.35 |
| 352.42 | 3.41 | 3.41 |
| 295.30 | 1.51 | 1.51 |
| 321.24 | 1.38 | 1.38 |
| 311.37 | 2.91 | 2.91 |
| 380.38 | 2.07 | 2.07 |
| 309.33 | 1.43 | 1.43 |
| 329.41 | 3.48 | 3.48 |
| 406.47 | 3.71 | 3.71 |
| 218.22 | 0.90 | 0.90 |
| 381.34 | 2.56 | 2.56 |
| 333.26 | 0.58 | 0.58 |
| 324.34 | 0.97 | 0.97 |
| 344.40 | 1.79 | 1.79 |
| 296.29 | 0.90 | 0.90 |
| 421.35 | 4.16 | 4.16 |
| 348.33 | 2.59 | 2.59 |
| 459.52 | 4.02 | 4.02 |
| 295.30 | 2.45 | 2.45 |
| 362.39 | 1.93 | 1.93 |
| 346.35 | 2.06 | 2.06 |
| 281.27 | 2.52 | 2.52 |
| 296.29 | 2.60 | 2.60 |
| 346.35 | 2.06 | 2.06 |
| 332.41 | 2.81 | 2.81 |
| 388.45 | 4.20 | 4.20 |
| 382.33 | 2.33 | 2.33 |
| 328.42 | 4.08 | 4.08 |
| 310.32 | 0.83 | 0.83 |
| 295.30 | 1.51 | 1.51 |
| 364.34 | 1.82 | 1.82 |
| 339.31 | 1.21 | 1.21 |
| 313.34 | 3.01 | 3.01 |
| 249.29 | 2.31 | 2.31 |
| 346.30 | 1.37 | 1.37 |
| 294.31 | 2.18 | 2.18 |
| 310.32 | 1.09 | 1.09 |
| 363.30 | 2.53 | 2.53 |
| 418.88 | 4.36 | 4.36 |
| 473.55 | 4.41 | 4.41 |
| 360.32 | 1.24 | 1.24 |
| 166.18 | 0.26 | 0.26 |